CEA Registry

Cost-Effectiveness Analysis (CEA) Registry - The CEA Registry is a comprehensive database of 9,080 cost-utility analyses on a wide variety of diseases and treatments published from 1976 to 2019.



Database Structure

The CEA Registry has three main sections:

  • Methods section, which contains one record for each article.
  • Ratio section, which contains one or more ratios for each article.
  • Utility Weight section, which contains none or one or more utility weight records for each article.

Data Collection Process

The published articles summarized in the Registry undergo a formalized review protocol. The analyses address a wide variety of diseases and treatments and all measure health effects in terms of quality-adjusted life years (QALYs). Two readers with training in decision analysis and cost-effectiveness analysis independently review each article and record information using a standardized set of forms and instructions. Data on over 40 variables are collected for each article.

1 Literature Search
2 Screening
3 Rejected Articles
4 Data Abstraction
5 Data Cleaning & Processing
6 CEA Registry Database

Information Collected

We report or describe:

  • Article Information including the type of intervention evaluated, the country of the analysis, the funding source, information regarding methodology including whether the article correctly calculated incremental cost-utility ratios, the analytic time horizon and analytic perspective and more.
  • Ratio Information including a description of the health intervention that is the subject of the analysis, comparator intervention to which it is compared and the population that is eligible for the intervention.
  • Utility Weight Information - We report the utility health state, the utility weight value, and when used, secondary literature sources relied upon to provide utility weight values.

Reading for the Registry

The registry’s contents are collected by our reviewers, who carefully audit and collect information from published cost- effectiveness articles. Given the increasing popularity of CEAs, we need more reviewers to keep the database up to date.


Why is a specific paper not in the Registry?

The paper may not satisfy our inclusion criteria which state that the paper must:

  1. Be published in English
  2. Be an original cost-effectiveness analysis
  3. Measure health benefits as QALYs

If you believe a paper satisfies these criteria and should be considered, let us know.

When will new data be posted?

The CEA Registry team posts newly collected data three times per year.

Are you going to include non-medical CUAs?

The Registry includes all CUAs indexed in Medline. There are a limited number of non-medical CUAs such as diet, injury prevention and environmental remediation.

Can you conduct additional analysis of the data for me?

Our Center provides fee-based analysis of the CEA Registry data. Financial terms will be determined on a case-by-case basis, depending on the scope and detail of analysis required. Please contact Julie Lannon for more information.

How should we cite the CEA Registry?

Center for the Evaluation of Value and Risk in Health. The Cost-Effectiveness Analysis Registry [Internet]. (Boston), Institute for Clinical Research and Health Policy Studies, Tufts Medical Center. Available from: www.cearegistry.org Accessed on [Date].